UBE2L3 (N-term) Peptide
产品名称： UBE2L3 (N-term) Peptide
英文名称： UBE2L3 (N-term) Peptide
产品编号： P0891
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of UBE2L3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human UBE2L3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Fine-mapping, genomic organization, and transcript analysis of the human ubiquitin-conjugating enzyme gene UBE2L3.
Moynihan TP, Cole CG, Dunham I, O'Neil L, Markham AF, Robinson PA.Genomics. 1998 Jul 1;51(1):124-7.
- 2.
- Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3.
Moynihan TP, Ardley HC, Leek JP, Thompson J, Brindle NS, Markham AF, Robinson PA.Mamm Genome. 1996 Jul;7(7):520-5.
- 3.
- Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5.
Nuber U, Schwarz S, Kaiser P, Schneider R, Scheffner M.J Biol Chem. 1996 Feb 2;271(5):2795-800.
- Applications
- Western Blot (Cell lysate)
- The UBE2L3 polyclonal antibody (Cat # PAB3893) is used in Western blot to detect UBE2L3 in HL-60 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with UBE2L3 polyclonal antibody (Cat # PAB3893) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Entrez GeneID:
- 7332
- Protein Accession#:
- UBC7_HUMAN
- Gene Name:
- UBE2L3
- Gene Alias:
- E2-F1,L-UBC,UBCH7,UbcM4
- Gene Description:
- ubiquitin-conjugating enzyme E2L 3
- Omim ID:
- 603721
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- ubiquitin carrier protein,ubiquitin-conjugating enzyme UBCH7,ubiquitin-protein ligase
- Gene Pathway
- Related Disease